GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621121
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cdk6
Name: cyclin-dependent kinase 6
Acc ID: CHEBI:28821
Term: piperine
Definition: A N-acylpiperidine that is piperidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum.
Chemical ID: MESH:C008922
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:7354016480464CTDpiperine inhibits the reaction [IL2 protein results in increased expression of CDK6 protein]

PMID:25655587
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.