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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 619573
Species: Mus musculus
CRRD Object: Gene
Symbol: Slc22a6
Name: solute carrier family 22 (organic anion transporter), member 6
Acc ID: CHEBI:28854
Term: 2,4-D
Definition: A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2 and 4 are substituted by chlorines.
Chemical ID: MESH:D015084
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a6increases uptakeISORGD:6195726480464CTDSLC22A6 protein results in increased uptake of 2, 4-Dichlorophenoxyacetic Acid

PMID:16857889, PMID:17255469
Slc22a6increases uptakeISORGD:693386480464CTDSLC22A6 protein results in increased uptake of 2, 4-Dichlorophenoxyacetic Acid

PMID:16857889
Slc22a6multiple interactionsISORGD:6195726480464CTDp-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased uptake of 2, 4-Dichlorophenoxyacetic Acid]

PMID:17255469
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.