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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620897
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Dusp1
Name: dual specificity phosphatase 1
Acc ID: CHEBI:29035
Term: manganese(2+)
Definition: A divalent metal cation in which the metal is manganese.
Chemical ID: MESH:D008345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7329556480464CTDManganese results in decreased expression of DUSP1 mRNA, Manganese results in decreased expression of DUSP1 protein

PMID:20589745
multiple interactionsISORGD:7329556480464CTD[Manganese co-treated with Lipopolysaccharides] results in decreased expression of DUSP1 mRNA, [Manganese co-treated with Lipopolysaccharides] results in decreased expression of DUSP1 protein

PMID:20589745
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.