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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2432
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cst3
Name: cystatin C
Acc ID: CHEBI:29036
Term: copper(2+)
Definition: An ion of copper carrying a double positive charge.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDCopper results in decreased expression of CST3 mRNA

PMID:22465980
multiple interactionsISORGD:104156480464CTD[ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of CST3 mRNA

PMID:15467011
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.