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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1304865
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Muc20
Name: mucin 20, cell surface associated
Acc ID: CHEBI:2948
Term: azathioprine
Definition: A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Chemical ID: MESH:D001379
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13125506480464CTDAzathioprine results in increased expression of MUC20 mRNA

PMID:22623647
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.