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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1307932
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cldn4
Name: claudin 4
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects localizationISORGD:13174146480464CTDsodium arsenite affects the localization of CLDN4 protein

PMID:24349408
decreases expressionISORGD:13174136480464CTDsodium arsenite results in decreased expression of CLDN4 mRNA

PMID:12634122
increases expressionISORGD:13174136480464CTDsodium arsenite results in increased expression of CLDN4 mRNA, sodium arsenite results in increased expression of CLDN4 protein

PMID:24349408
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.