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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1591241
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Srrt
Name: serrate, RNA effector molecule
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:16048116480464CTDsodium arsenite results in increased expression of SRRT mRNA, sodium arsenite results in increased expression of SRRT protein

PMID:23219847, PMID:26404762, PMID:28595984
multiple interactionsISORGD:16048116480464CTD3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [sodium arsenite results in increased expression of SRRT protein], 4(2'-aminoethyl)amino-1, 8-dimethylimidazo(1, 2-a)quinoxaline inhibits the reaction [sodium arsenite results in increased expression of SRRT protein], pyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of SRRT protein], SB 203580 inhibits the reaction [sodium arsenite results in increased expression of SRRT protein], tetramethylpyrazine inhibits the reaction [sodium arsenite results in increased expression of SRRT protein], U 0126 inhibits the reaction [sodium arsenite results in increased expression of SRRT protein]

PMID:23219847, PMID:26404762
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.