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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621821
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Fen1
Name: flap structure-specific endonuclease 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDsodium arsenite results in increased expression of FEN1 protein

PMID:19072884
decreases expressionISORGD:7326796480464CTDsodium arsenite results in decreased expression of FEN1 mRNA

PMID:12377979
increases expressionISORGD:7326796480464CTDsodium arsenite results in increased expression of FEN1 mRNA

PMID:28595984
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.