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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2414
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cryab
Name: crystallin, alpha B
Acc ID: CHEBI:29693
Term: thiostrepton
Definition: A heterodetic cyclic peptide, in which the cyclisation step involves a formal lactonisation between the carboxy group of a quinaldic acid-based residue and a secondary alcohol. An antibiotic that inhibits bacterial protein synthesis. Also acts as an antitumor agent.
Chemical ID: MESH:D013883
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7375186480464CTDThiostrepton results in increased expression of CRYAB mRNA

PMID:22321511
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