GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 62081
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Hes1
Name: hes family bHLH transcription factor 1
Acc ID: CHEBI:29699
Term: tunicamycin
Definition: A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety.
Chemical ID: MESH:D014415
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:623736480464CTDTunicamycin results in increased expression of HES1 mRNA

PMID:22115781
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.