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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1311858
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Abhd4
Name: abhydrolase domain containing 4, N-acyl phospholipase B
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abhd4increases expressionISORGD:13235346480464CTDBenzo(a)pyrene results in increased expression of ABHD4 mRNA

PMID:20106945, PMID:21632981, PMID:22316170, PMID:26238291
Abhd4increases expressionISORGD:13235356480464CTDBenzo(a)pyrene results in increased expression of ABHD4 mRNA

PMID:15034205, PMID:19770486, PMID:21715664
Abhd4multiple interactionsISORGD:13235356480464CTDBenzo(a)pyrene promotes the reaction [AHR protein binds to ABHD4 promoter]

PMID:19654925
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.