Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 67378
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ncam1
Name: neural cell adhesion molecule 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects methylationISORGD:7340226480464CTDBenzo(a)pyrene affects the methylation of NCAM1 intron

PMID:30157460
decreases expressionISORGD:7369886480464CTDBenzo(a)pyrene results in decreased expression of NCAM1 mRNA

PMID:20713471
increases expressionISORGD:7369886480464CTDBenzo(a)pyrene results in increased expression of NCAM1 mRNA

PMID:22228805
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.