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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621821
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Fen1
Name: flap structure-specific endonuclease 1
Acc ID: CHEBI:30185
Term: zinc(0)
Definition: An elemental zinc that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7326806480464CTD[Zinc deficiency promotes the reaction [TRP53 gene mutant form results in increased susceptibility to nitrosobenzylmethylamine]] which results in decreased expression of FEN1 mRNA

PMID:12517797
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.