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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69224
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gpx3
Name: glutathione peroxidase 3
Acc ID: CHEBI:30314
Term: (R)-lipoic acid
Definition: The (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties.
Chemical ID: MESH:D008063
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13438586480464CTDThioctic Acid results in increased expression of GPX3 mRNA

PMID:23649336
multiple interactionsISORGD:13438586480464CTD[Paraquat co-treated with Thioctic Acid] results in increased expression of GPX3 mRNA

PMID:23649336
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.