GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 735047
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nedd4l
Name: neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Acc ID: CHEBI:30563
Term: silicon dioxide
Definition: A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens.
Chemical ID: MESH:D012822
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:13442036480464CTDSilicon Dioxide analog results in decreased expression of NEDD4L mRNA

PMID:25895662
increases expressionISOCRRD:13442036480464CTDSilicon Dioxide results in increased expression of NEDD4L mRNA

PMID:25351596
increases expressionISOCRRD:15511616480464CTDSilicon Dioxide results in increased expression of NEDD4L mRNA

PMID:19073995
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.