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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 70924
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Pdzk1
Name: PDZ domain containing 1
Acc ID: CHEBI:30614
Term: benzo[a]pyrene diol epoxide I
Definition: An epoxide that has formula C20H14O3.
Chemical ID: MESH:D015123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7328236480464CTD7, 8-Dihydro-7, 8-dihydroxybenzo(a)pyrene 9, 10-oxide results in decreased expression of PDZK1 mRNA

PMID:26238291
increases expressionISORGD:7328236480464CTD7, 8-Dihydro-7, 8-dihydroxybenzo(a)pyrene 9, 10-oxide results in increased expression of PDZK1 mRNA

PMID:20382639
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.