Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2835
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Hsd11b2
Name: hydroxysteroid 11-beta dehydrogenase 2
Acc ID: CHEBI:31429
Term: Colforsin dapropate hydrochloride
Definition: null
Chemical ID: MESH:D005576
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7374686480464CTDColforsin results in increased expression of HSD11B2 mRNA, Colforsin results in increased expression of HSD11B2 protein

PMID:24361490, PMID:29802914
multiple interactionsISORGD:7374686480464CTDColforsin inhibits the reaction [1, 7-dimethylxanthine results in decreased expression of and results in decreased activity of HSD11B2 protein], Colforsin inhibits the reaction [1, 7-dimethylxanthine results in decreased expression of HSD11B2 mRNA], Colforsin inhibits the reaction [Caffeine results in decreased expression of and results in decreased activity of HSD11B2 protein], Colforsin inhibits the reaction [Caffeine results in decreased expression of HSD11B2 mRNA], Colforsin inhibits the reaction [Ethanol results in decreased expression of HSD11B2 mRNA], Colforsin inhibits the reaction [Ethanol results in decreased expression of HSD11B2 protein], Ethanol inhibits the reaction [Colforsin results in increased expression of HSD11B2 mRNA], Ethanol inhibits the reaction [Colforsin results in increased expression of HSD11B2 protein]

PMID:22701600, PMID:29802914
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.