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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1344013
Species: Homo sapiens
CRRD Object: Gene
Symbol: PBDC1
Name: polysaccharide biosynthesis domain containing 1
Acc ID: CHEBI:31653
Term: glafenine
Definition: A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.
Chemical ID: MESH:D005897
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:15625026480464CTDGlafenine results in increased expression of PBDC1 mRNA

PMID:24136188
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