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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737494
Species: Homo sapiens
CRRD Object: Gene
Symbol: SYP
Name: synaptophysin
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:113736480464CTDlead acetate results in decreased expression of SYP protein

PMID:27771255
decreases expressionISORGD:38026480464CTDlead acetate results in decreased expression of SYP protein

PMID:17047031, PMID:20375082
increases expressionISORGD:38026480464CTDlead acetate results in increased expression of SYP protein

PMID:27984133
multiple interactionsISORGD:38026480464CTDBDNF protein inhibits the reaction [lead acetate results in decreased expression of SYP protein]

PMID:20375082
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.