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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3449
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Sirpa
Name: signal-regulatory protein alpha
Acc ID: CHEBI:32234
Term: titanium dioxide
Definition: A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.
Chemical ID: MESH:C009495
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:102436480464CTDtitanium dioxide results in decreased expression of SIRPA mRNA

PMID:29264374
increases expressionISORGD:102436480464CTDtitanium dioxide results in increased expression of SIRPA mRNA

PMID:23409001, PMID:23557971
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.