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CRRD ID: 3543
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Rbp1
Name: retinol binding protein 1
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of RBP1 mRNA

PMID:19162173, PMID:22484513
increases expressionISORGD:112216480464CTDpirinixic acid results in increased expression of RBP1 mRNA

multiple interactionsISORGD:112216480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of RBP1 mRNA, PPARA protein inhibits the reaction [pirinixic acid results in increased expression of RBP1 mRNA]

PMID:17950772, PMID:19710929
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.