GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 61945
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Per2
Name: period circadian regulator 2
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:622386480464CTDpirinixic acid results in decreased expression of PER2 mRNA

PMID:20813756, PMID:23811191
multiple interactionsISOCRRD:622386480464CTD[pirinixic acid co-treated with PPARA] results in decreased expression of PER2 mRNA

PMID:20813756
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.