Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620585
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Elovl6
Name: ELOVL fatty acid elongase 6
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityEXP 6480464CTDpirinixic acid results in increased activity of ELOVL6 protein

PMID:15654130
increases expressionEXP 6480464CTDpirinixic acid results in increased expression of ELOVL6 mRNA

PMID:15654130, PMID:27665778
decreases expressionISORGD:13322056480464CTDpirinixic acid results in decreased expression of ELOVL6 mRNA

PMID:18445702
increases expressionISORGD:13322056480464CTDpirinixic acid results in increased expression of ELOVL6 mRNA

PMID:16790840, PMID:18467677
multiple interactionsISORGD:13322056480464CTDPPARA protein affects the reaction [pirinixic acid results in increased expression of ELOVL6 mRNA], PPARA protein promotes the reaction [pirinixic acid results in increased expression of ELOVL6 mRNA]

PMID:16790840, PMID:18467677
multiple interactionsISORGD:13452216480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ELOVL6 mRNA

PMID:19710929
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.