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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737414
Species: Mus musculus
CRRD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7374136480464CTDchromium hexavalent ion results in decreased expression of CDH1 mRNA, chromium hexavalent ion results in decreased expression of CDH1 protein

PMID:23518002, PMID:27323401
multiple interactionsISORGD:7374136480464CTDCAT protein inhibits the reaction [chromium hexavalent ion results in decreased expression of CDH1 protein], chromium hexavalent ion promotes the reaction [HDAC1 protein binds to CDH1 promoter], trichostatin A inhibits the reaction [chromium hexavalent ion results in decreased expression of CDH1 protein]

PMID:23518002
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.