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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1317218
Species: Homo sapiens
CRRD Object: Gene
Symbol: CHCHD5
Name: coiled-coil-helix-coiled-coil-helix domain containing 5
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CHCHD5increases expressionISORGD:13078096480464CTDbisphenol A results in increased expression of CHCHD5 mRNA

PMID:25181051
CHCHD5increases methylationISORGD:13078096480464CTDbisphenol A results in increased methylation of CHCHD5 gene

PMID:28505145
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.