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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1349606
Species: Homo sapiens
CRRD Object: Gene
Symbol: IL1RAPL2
Name: interleukin 1 receptor accessory protein like 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:15617616480464CTDbisphenol A results in decreased expression of IL1RAPL2 mRNA

PMID:25181051
increases methylationISORGD:15574336480464CTDbisphenol A results in increased methylation of IL1RAPL2 promoter

PMID:27312807
increases methylationISORGD:15617616480464CTDbisphenol A results in increased methylation of IL1RAPL2 gene

PMID:28505145
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.