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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1561092
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Mdm1
Name: Mdm1 nuclear protein
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of MDM1 mRNA

PMID:25181051
multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of MDM1 mRNA

PMID:26496021
affects expressionISORGD:13525156480464CTDbisphenol A affects the expression of MDM1 mRNA

PMID:22574217
multiple interactionsISORGD:13525156480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MDM1 mRNA

PMID:28628672
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.