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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 619573
Species: Mus musculus
CRRD Object: Gene
Symbol: Slc22a6
Name: solute carrier family 22 (organic anion transporter), member 6
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a6decreases expressionISORGD:693386480464CTDbisphenol A results in decreased expression of SLC22A6 mRNA

PMID:25181051, PMID:30816183
Slc22a6increases expressionISORGD:693386480464CTDbisphenol A results in increased expression of SLC22A6 mRNA

PMID:17010207
Slc22a6multiple interactionsISORGD:6195726480464CTDbisphenol A promotes the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]

PMID:27989701
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.