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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620594
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ccr4
Name: C-C motif chemokine receptor 4
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDCapsaicin results in increased expression of CCR4 protein

PMID:22150557
multiple interactionsEXP 6480464CTD[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCR4 protein], Naproxen inhibits the reaction [Capsaicin results in increased expression of CCR4 protein], Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]

PMID:22150557
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.