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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 11250
Species: Mus musculus
CRRD Object: Gene
Symbol: Rxra
Name: retinoid X receptor alpha
Acc ID: CHEBI:338412
Term: (-)-anisomycin
Definition: An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
Chemical ID: MESH:D000841
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases phosphorylationEXP 6480464CTDAnisomycin results in increased phosphorylation of RXRA protein

PMID:16038797
multiple interactionsEXP 6480464CTDpyrazolanthrone inhibits the reaction [Anisomycin results in increased phosphorylation of RXRA protein]

PMID:16038797
increases phosphorylationISORGD:7369296480464CTDAnisomycin results in increased phosphorylation of RXRA protein

PMID:16184197
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.