GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 61856
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gabra2
Name: gamma-aminobutyric acid type A receptor alpha2 subunit
Acc ID: CHEBI:3387
Term: carbamazepine
Definition: A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Chemical ID: MESH:D002220
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityEXP 6480464CTDCarbamazepine results in increased activity of GABRA2 protein

PMID:18717705
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.