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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2835
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Hsd11b2
Name: hydroxysteroid 11-beta dehydrogenase 2
Acc ID: CHEBI:34025
Term: 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane
Definition: A bisphenol that has formula C14H11Cl3O2.
Chemical ID: MESH:C404910
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases activityEXP 6480464CTD2, 2-bis(4-hydroxyphenyl)-1, 1, 1-trichloroethane results in decreased activity of HSD11B2 protein

PMID:23333641
decreases activityISORGD:7374686480464CTD2, 2-bis(4-hydroxyphenyl)-1, 1, 1-trichloroethane results in decreased activity of HSD11B2 protein

PMID:23333641
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.