GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1307751
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Srebf2
Name: sterol regulatory element binding transcription factor 2
Acc ID: CHEBI:34202
Term: 2,2',4,4',5,5'-hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C014024
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:7309736480464CTD2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of SREBF2 mRNA

PMID:20005886, PMID:21851831
multiple interactionsISOCRRD:7309736480464CTDTetrachlorodibenzodioxin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of SREBF2 mRNA]

PMID:21851831
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.