GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 735047
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nedd4l
Name: neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Acc ID: CHEBI:34202
Term: 2,2',4,4',5,5'-hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C014024
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:15511616480464CTD[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of NEDD4L mRNA

PMID:25510870
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.