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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737414
Species: Mus musculus
CRRD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7374136480464CTD3, 4, 5, 3', 4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA

PMID:28284859
multiple interactionsISORGD:7374136480464CTDAcetylcysteine inhibits the reaction [3, 4, 5, 3', 4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA], AHR mRNA promotes the reaction [3, 4, 5, 3', 4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA], fulvestrant inhibits the reaction [3, 4, 5, 3', 4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA], PKM protein promotes the reaction [3, 4, 5, 3', 4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA], WP1066 inhibits the reaction [3, 4, 5, 3', 4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]

PMID:28284859
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.