GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 708419
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Brinp2
Name: BMP/retinoic acid inducible neural specific 2
Acc ID: CHEBI:34567
Term: benzo[e]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. It is listed as a Group 3 carcinogen by the IARC.
Chemical ID: MESH:C026487
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases methylationISOCRRD:16056456480464CTDbenzo(e)pyrene results in increased methylation of FAM5B exon

benzo(e)pyrene results in increased methylation of FAM5B intron

PMID:30157460
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.