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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 61312
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Timp2
Name: TIMP metallopeptidase inhibitor 2
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of TIMP2 mRNA, [Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of TIMP2 mRNA, [Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of TIMP2 protein

PMID:12015029, PMID:28943392
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