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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620196
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Mmp13
Name: matrix metallopeptidase 13
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:15522436480464CTDDiethylnitrosamine results in increased expression of MMP13 mRNA

PMID:16284949, PMID:24535843
multiple interactionsISOCRRD:15522436480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of MMP13 mRNA

PMID:24535843
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.