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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 628729
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Fkbp4
Name: FKBP prolyl isomerase 4
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects response to substanceISORGD:15516326480464CTDFKBP4 protein affects the susceptibility to Paraquat

PMID:20713718
multiple interactionsISORGD:15516326480464CTD[Paraquat co-treated with Maneb] results in decreased expression of FKBP4 mRNA

PMID:18386188
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.