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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3382
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ppp3ca
Name: protein phosphatase 3 catalytic subunit alpha
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDCadmium Chloride results in decreased expression of PPP3CA mRNA

PMID:31077537
multiple interactionsEXP 6480464CTD[Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of PPP3CA mRNA

PMID:31077537
decreases expressionISORGD:7309006480464CTDCadmium Chloride results in decreased expression of PPP3CA mRNA

PMID:18560533
increases expressionISORGD:7309006480464CTDCadmium Chloride results in increased expression of PPP3CA mRNA

PMID:12160620
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.