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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2874
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Igfbp3
Name: insulin-like growth factor binding protein 3
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDperfluorooctanoic acid results in decreased expression of IGFBP3 mRNA

PMID:19162173
increases expressionISORGD:7360426480464CTDperfluorooctanoic acid results in increased expression of IGFBP3 mRNA

PMID:25868421
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