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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620575
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Apaf1
Name: apoptotic peptidase activating factor 1
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7332946480464CTDcobaltous chloride results in increased expression of APAF1 mRNA

PMID:24265542
multiple interactionsISORGD:7332946480464CTD[cobaltous chloride co-treated with 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole] results in increased expression of APAF1 mRNA

PMID:24265542
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.