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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620575
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Apaf1
Name: apoptotic peptidase activating factor 1
Acc ID: CHEBI:35828
Term: arsenic(3+)
Definition: A monoatomic arsenic that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7332936480464CTDArsenic results in increased expression of APAF1 mRNA

PMID:19945496
multiple interactionsISORGD:7332936480464CTDArsenic affects the reaction [GSTO1 gene alternative form results in increased expression of APAF1 mRNA]

PMID:22293942
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.