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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620575
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Apaf1
Name: apoptotic peptidase activating factor 1
Acc ID: CHEBI:37187
Term: lead nitrate
Definition: A lead coordination entity that has formula N2O6Pb.
Chemical ID: MESH:C017461
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7332946480464CTDlead nitrate results in decreased expression of APAF1 protein

PMID:23451106
multiple interactionsISORGD:7332946480464CTDmangiferin inhibits the reaction [lead nitrate results in decreased expression of APAF1 protein]

PMID:23451106
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.