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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621032
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nr0b2
Name: nuclear receptor subfamily 0, group B, member 2
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7328746480464CTDClofibrate results in decreased expression of NR0B2 mRNA

PMID:28973556
increases expressionISORGD:7328746480464CTDClofibrate results in increased expression of NR0B2 mRNA

PMID:29175453
multiple interactionsISORGD:7328746480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of NR0B2 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of NR0B2 mRNA]

PMID:17585979
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.