GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 727915
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cyp27a1
Name: cytochrome P450, family 27, subfamily a, polypeptide 1
Acc ID: CHEBI:37659
Term: oleanolic acid
Definition: A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3.
Chemical ID: MESH:D009828
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:15504756480464CTDOleanolic Acid results in decreased expression of CYP27A1 mRNA

PMID:23948738
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.