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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621612
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nts
Name: neurotensin
Acc ID: CHEBI:38912
Term: Ro 31-8220
Definition: An imidothiocarbamic ester that has formula C25H23N5O2S.
Chemical ID: MESH:C064758
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityISORGD:13190926480464CTDRo 31-8220 results in increased activity of NTS protein

PMID:18313772
multiple interactionsISORGD:13190926480464CTDRo 31-8220 affects the reaction [NTS protein results in increased chemical synthesis of Inositol Phosphates], Tetradecanoylphorbol Acetate inhibits the reaction [Ro 31-8220 results in increased activity of NTS protein]

PMID:18313772
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.