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CRRD ID: 2933
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Itpr1
Name: inositol 1,4,5-trisphosphate receptor, type 1
Acc ID: CHEBI:39421
Term: perfluorooctane-1-sulfonic acid
Definition: A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines.
Chemical ID: MESH:C076994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDperfluorooctane sulfonic acid results in increased expression of ITPR1 mRNA

multiple interactionsISOCRRD:108216480464CTDperfluorooctane sulfonic acid inhibits the reaction [ITPR1 protein binds to HSPA9 protein binds to VDAC1 protein]

perfluorooctane sulfonic acid promotes the reaction [ITPR1 protein binds to AKT1 protein]

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