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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737494
Species: Homo sapiens
CRRD Object: Gene
Symbol: SYP
Name: synaptophysin
Acc ID: CHEBI:39421
Term: perfluorooctane-1-sulfonic acid
Definition: A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines.
Chemical ID: MESH:C076994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:38026480464CTDperfluorooctane sulfonic acid affects the expression of SYP mRNA, perfluorooctane sulfonic acid affects the expression of SYP protein

PMID:20136073, PMID:20937303
increases expressionISORGD:113736480464CTDperfluorooctane sulfonic acid results in increased expression of SYP protein

PMID:19211617
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.