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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1316368
Species: Homo sapiens
CRRD Object: Gene
Symbol: ZEB2
Name: zinc finger E-box binding homeobox 2
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of ZEB2 mRNA

PMID:23179753, PMID:24383497, PMID:24935251, PMID:27188386, PMID:28001369
increases expressionEXP 6480464CTDValproic Acid results in increased expression of ZEB2 mRNA

PMID:28001369
affects splicingISORGD:13072726480464CTDValproic Acid affects the splicing of ZEB2 mRNA

PMID:29427782
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.